WebPatients received two to four cycles (repeated every 3 weeks) of cisplatin (50 mg/m2), doxorubicin (50 mg/m2), and cyclophosphamide (500 mg/m2) followed by a total dosage of 54 Gy to the primary tumor and regional lymph nodes for patients with a stable, partial, or complete response to chemotherapy. Results: WebFeb 25, 2024 · Patients were randomly assigned 1:1 to either cisplatin 75 mg/m 2 intravenously (IV) × 4 cycles or to AC (doxorubicin 60 mg/m 2 IV and cyclophosphamide 600 mg/m 2 IV) × 4 cycles every 2 (dose dense [dd]) or 3 weeks. Randomization was stratified by tumor ER status (≥ 1% v < 1%) and by treatment site.
Synergistic cytotoxicity of Bcl-xL inhibitor, gossypol and ...
WebTreatment of co-culture of immortalized human foreskin fibroblasts and MCF7 mammary cancer cells with azathioprine, carboplatin, cisplatin, cyclophosphamide, doxorubicin, 5-fluorouracil, gemcitabine, methotrexate, 6-mercaptopurine, mitoxantrone, 6-thioguanine, and taxol led to the activation of fibroblasts and their transformation to the ... WebNov 2, 2024 · Cisplatin/Doxorubicin/ Paclitaxel 2,20,22,24,b,j ... A randomized comparison of doxorubicin alone versus doxorubicin plus cyclophosphamide in the management of advanced or recurrent endometrial ... philosophy and business
Cyclophosphamide - National Library of Medicine Search Results
WebThe addition of cisplatin to doxorubicin and cyclophosphamide increased toxicity without increasing the antitumor activity previously reported for the two-drug combination. … WebOct 5, 2014 · The addition of cisplatin to cyclophosphamide and doxorubicin (CAP) has been recently associated with overall response rates of 57% to 100% and complete response rates of 26% to 75% in small series of patients (Creagan, Woods et al., 1983;Alberts, Manning et al., 1981;Eisenberger, 1985). Cisplatin is known to have an … Web3rd occurrence: Reduce doxorubicin, cyclophosphamide and cisplatin by 50% 4th occurrence: Withhold chemotherapy Delay treatment until toxicity has resolved to Grade 1 or less and reduce doses for subsequent cycles as follows: 1st occurrence: Reduce doxorubicin, cyclophosphamide and cisplatin by 50% 2nd occurrence: Withhold … philosophy and critical thinking